Hormone Therapy

Hormone therapy is sometimes used after surgery to decrease the change of the cancer returning or after it has already spread to shrink and contain it. This therapy is recommended for women who have a type of breast cancer that is sensitive to hormones—estrogen receptor positive (ER positive) and progesterone receptor positive (PR positive ) cancers. There are three primary ways to block hormones:

Medicines that block hormones from attaching to cells: Tamoxifen is the most commonly used drug to block estrogen from attaching to an estrogen receptor in cancer cells, which slows the growth and can kill cancer cells. This drug can be used in both pre- and post-menopausal women.

Side Effects

  • Fatigue
  • Hot flashes
  • Night sweats
  • Vaginal dryness
  • Cataracts
  • Blood clots
  • Stroke
  • Uterine cancer

Medicines that stop the production of estrogen after menopause, such as a group of drugs called aromatase inhibitors that block the action of an enzyme that converts androgens in the body to estrogen.

Side Effects

  • Joint and muscle pain
  • Bone thinning or osteoporosis

Medicines or surgery that stops hormone production in the ovaries for premenopausal women. Additionally some women can have surgery in the form of prophylactic oophorectomy to surgically stop hormone production.

Awareness

Read this NY Times piece featuring Nt’l Race Host Committee member Megan Neforos: click here

Research

The 2015-2016 Research Grants and Awards booklet is now available. For more information, click here.

Education

The next Ovarian Cancer Survivors Course is Sept. 12 in Duarte, Calif. For more information, click here.