Vaginal cancer begins in the vagina, the muscular tube, also called the birth canal, that connects the outer genitalia to the uterus. Most of these cancers are in the lining (squamous epthelilum) of the vagina and usually affect between women 50-70 years old. Primary vaginal cancer is one of the rarest gynecologic cancers.
Because many vaginal cancers are associated with the Human Papillomavirus (HPV) types 16 and 18, vaginal cancer can be prevented by the vaccinations advocated for the prevention of cervical cancer.
The Foundation offers educational materials that explore this in more depth.